57 Plasma Cells

Michelle To and Valentin Villatoro

Notes: The maturation of a lymphocyte to a plasma cell marks the production of immunoglobulins. Lymphocytes that mature into plasma cells are of B lineage.1

 

Nucleus-to-Cytoplasm Ratio:  2:1 to 1:1 2

 

Nucleoli: None 1,2

 

Nucleus:1,2

Round or oval

Eccentrically located

Coarse, clumpy, dark purple staining chromatin

 

Cytoplasm:1,2

Abundant

Darkly basophilic

Perinuclear (clear) zone may be seen around the nucleus (Representing the golgi body)

Vacuoles may be present

 

Normal % in Bone Marrow: 0-1% 1,2

 

Normal % in Peripheral Blood: 0% 1,2


References:

1. Williams L, Finnegan K. Lymphocytes. In: Clinical laboratory hematology. 3rd ed. New Jersey: Pearson; 2015. p. 122-43.

2. Rodak BF, Carr JH. Lymphocyte maturation. In: Clinical hematology atlas. 5th ed. St. Louis, Missouri: Elsevier Inc.; 2017. p. 79-88.

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A Laboratory Guide to Clinical Hematology by Michelle To and Valentin Villatoro is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, except where otherwise noted.

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