Notes: Develop and are mainly found in the bone marrow. Maturation usually involves the division of nucleus but not the division of the cytoplasm, this gives rise to a polyploid cell.1
Nucleus-to-Cytoplasm Ratio: Variable 2
Nucleoli: N/A 2
Variable number of lobes (2-32)2
Blue to purple cytoplasm
Reddish blue granules may be visible
% in Bone Marrow: 5-10 (per field at 100x magnification)2
% in Peripheral Blood: None
1. Lynne Williams J. The Platelet. In: Clinical laboratory hematology. 3rd ed. New Jersey: Pearson; 2015. p. 144–53.
2. Rodak BF, Carr JH. Megakaryocyte maturation. In: Clinical hematology atlas. 5th ed. St. Louis, Missouri: Elsevier Inc.; 2017. p. 31-40.