60 Megakaryocytes

Michelle To and Valentin Villatoro

Notes: Develop and are mainly found in the bone marrow. Maturation usually involves the division of nucleus but not the division of the cytoplasm, this gives rise to a polyploid cell.1

 

Nucleus-to-Cytoplasm Ratio: Variable 2

 

Nucleoli: N/A 2

 

Nucleus:

Variable number of lobes (2-32)2

 

Cytoplasm:2

Abundant

Blue to purple cytoplasm

Reddish blue granules may be visible

 

% in Bone Marrow: 5-10 (per field at 100x magnification)2

 

% in Peripheral Blood: None


References:

1. Lynne Williams J. The Platelet. In: Clinical laboratory hematology. 3rd ed. New Jersey: Pearson; 2015. p. 144–53.

2. Rodak BF, Carr JH. Megakaryocyte maturation. In: Clinical hematology atlas. 5th ed. St. Louis, Missouri: Elsevier Inc.; 2017. p. 31-40.

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A Laboratory Guide to Clinical Hematology by Michelle To and Valentin Villatoro is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, except where otherwise noted.

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