Crystals appear as a combination of sickle cells and hemoglobin C crystals. They are dark red inclusions with blunt ended projections.1 The crystals are longer than Hemoglobin C crystals, but shorter and thicker than Hemoglobin S.
Hemoglobin S and hemoglobin C
Associated Disease/Clinical States:1
Hemoglobin SC Disease (compound heterozygosity)
1. Rodak BF, Carr JH. Variations in shape and distribution of erythrocytes. In: Clinical hematology atlas. 5th ed. St. Louis, Missouri: Elsevier Inc.; 2017. p. 93-106.